Structural and Biochemical Evidence that Scrapie-associated Fibrils Assemble in vivo
نویسندگان
چکیده
منابع مشابه
Tubulofilaments in negatively stained scrapie-infected brains: relationship to scrapie-associated fibrils.
A simple method was devised for negative-stain transmission electron microscopy of brain infected with the agent of scrapie. Brains of infected hamsters contained large masses of tubulofilamentous structures with irregular fuzzy surfaces. Brains of mice infected with Creutzfeldt-Jakob disease agent contained similar tubulofilaments in smaller numbers. The abnormal tubulofilaments resembled but ...
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ژورنال
عنوان ژورنال: Journal of General Virology
سال: 1989
ISSN: 0022-1317,1465-2099
DOI: 10.1099/0022-1317-70-1-25